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Justapapillar Duodenal Gastrointestinal Stromal Tumor (gist) Local Resection: A Case Report

Daniel Navarini, Antônio Benincá Albuquerque, André Luca Boeira Rovani, Thiago Beltrame Rohden, Diego Reffatti, André Emanuel Lunkes de Oliveira, Christopher Naher, Felipe Baldus, Lais Antunes de Lima, Vírginia de Carli de Moura, Felipe Thome dos Santos, Ramir Luan Perin, Carlos Augusto Scussel Madalosso

Abstract


Introduction: Gastrointestinal stromal tumors (GISTs) are the most frequent non-epithelial tumors of the gastrointestinal tract (GIT). The most common location is the stomach, followed by small intestine, being very rare the cases of duodenal origin, where it can cause digestive bleeding and anemia. The surgical resection of the tumor is the gold-standard treatment and the definitive diagnosis is based on immunohistochemical analysis of the surgical specimen.

Case presentation: A case of exophytic and endophytic GIST located in the second portion of the duodenum, one centimeter below the duodenal papilla, was reported in a 33-year-old female patient.

Conclusion: The gold-standard treatment is surgical resection of the tumor with negative margins (R0), with no need for lymphadenectomy. Local lesion resection or duodenopancreatectomy can be performed. Duodenopancreatectomy, unlike local resection of the lesion, is associated with increased length of hospital stay and longer intraoperative time. Therefore, it should be reserved for lesions that cannot be resected locally. Fortunately, a local resection was performed, which have a more favorable prognosis.



Keywords


Gastrointestinal Stromal Tumors; Justapapillar duodenal GIST; Gastrointestinal neoplasms

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