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Extra-skeletal Ewing’s Sarcoma of Caecum Causing Intussusception: First such Reported Case

Paritosh Gupta, Dhruv Nayan Kundra, Amanpriya Khanna, Aakanksha Aggarwal

Abstract


Introduction: Ewing’s sarcoma is a tumor of primitive cells which primarily affects long bones. Extra-skeletal Ewing’s sarcoma has been rarely reported in small bowel. Its presentation can be varied but it is an extremely unlikely cause of an Ileo-Colic Intussusception as seen in present case.

Case Presentation: A 32 years old male patient presented with symptoms suggestive of bowel obstruction. CT scan was suggestive of Ileo-colic intussusception. Patient underwent diagnostic laparoscopy and right hemicolectomy. Histopathology examination of specimen revealed Ewing sarcoma of colon.

Conclusion: Extra-skeletal Ewing’s sarcoma is a rare entity. To the best of our knowledge this is the first reported case in English literature, of a Caecal Ewing’s sarcoma causing Intussusception. Further study of such cases may help in better understanding and establishing treatment protocol for this condition.


Keywords


Extra-skeletal Ewing’s Sarcoma; Caecal; Intussusception

References


Kim SK, Park YK. Ewing sarcoma: a chronicle of molecular pathogenesis. Hum Pathol. 2016, 55:91-100

Dehner LP. Primitive neuroectodermaltumor and Ewing’s sarcoma. Am J Surg Pathol. 1993, 17(1):1-13. 3.

Dehner LP. The evolution of the diagnosis and understanding of primitive and embryonic neoplasms in children: living through an epoch. Mod Pathol. 1998, 11(7):669-85

Ahmad R, Mayol BR, Davis M, Rougraff BT. ExtraskeletalEwing_s sarcoma. Cancer. 1999, 85: 725-731

Minniti A, Jougon J, Barone M, Belleannee G, Velly JF. A case of extraskeletalEwing_s sarcoma of the thoracic wall. Il Giornale di chirurgia. 2000, 21:450-452

Maesawa C, Iijima S, Sato N, Yoshinori N, Suzuki M, Tarusawa M, Ishida K, Tamura G, Saito K, Masuda T. Esophagealextraskeletal Ewing's sarcoma. Hum Pathol. 2002, 33:130-132

Czekalla R, Fuchs M, Stolzle A, Nerlich A, Poremba C, Schaefer KL, Weirich G, Hofler H, Schneller F, Peschel C, Siewert JR, Schepp W. Peripheral primitive neuroectodermaltumor of the stomach in a 14-year-old boy: a case report. Eur J Gastroenterol Hepatol. 2004, 16:1391400

Colecchia M, Dagrada G, Poliani PL, Messina A, Pilotti S. Primary primitive peripheral neuroectodermaltumor of the prostate. Immunophenotypic and molecular study of a case. Arch Pathol Lab Med. 2003, 127: e190-e193

Padma M, Lakshmi RR. Extraskeletal Ewing’s Sarcoma of the small bowel. Int J Med Sci Cli Inv. 2015, 2(1):645-664

LorRandall R, Calvert GT, Spraker HL, Lessnick SL. Ewing’s Sarcoma Family of Tumors (ESFT): ESUN. 2011:3-4

Pradhan A, Grimer RJ, Spooner D, et al. Oncological outcomes of patients with Ewing’s sarcoma: Is there a difference between skeletal and extra-skeletal Ewing’s sarcoma? J Bone Joint Surg Br. 2011, 93(4):531-536

Applebaum MA, Worch J, Matthay KK, et al. Clinical features and outcomes in patients with extraskeletal Ewing sarcoma. Cancer. 2011, 117(13):3027-3032

Grünewald TGP, Cidre-aranaz F, Surdez D, et al. Ewing sarcoma. Nat Rev Dis Primers. 2018, 4(1):5

Yagnik D, Dawka S. Extraskeletal Ewing’s sarcoma/peripheral primitive neuroectodermaltumor of the small bowel presenting with gastrointestinal perforation. Clinical and Experimental Gastroenterology. 2019, 12:279-285

Li et al. Primary Ewing’s sarcoma/primitive neuroectodermaltumor of the ileum: case report of a 16-year-old Chinese female and literature review. Diagnostic Pathology. 2017, 12(1):37.

Gaspar N, Hawkins DS, Dirksen U, Lewis IJ, Ferrari S, Le Deley MC, et al. Ewing Sarcoma: Current Management and Future Approaches Through Collaboration. J Clin Oncol. 2015, 33(27):3036-3046

Biermann JS. Updates in the treatment of bone cancer. J Natl Compr Canc Netw. 2013, 11(5 Suppl):681-683


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