Epstein Barr Virus negative Lymphoepithelial Carcinoma Involving the Maxillary Sinus: A Rare Case Report
Abstract
Introduction: Lymphoepithelial carcinoma (LEC) is one of the rare malignancies involving the head and neck region. It is common in Eskimos and Chinese population with Epstein Barr virus association. Standard treatment protocol is not in place owing to the rarity of this tumor.
Case Presentation: The present case is a LEC involving the right maxillary sinus not associated with Epstein Barr Virus (EBV) and first of its kind presentation in the Indian population. Lack of awareness, nonaffordability and poor patient compliance resulted in poor response to radiotherapy. The patient succumbed within fourteen months of diagnosis.
Conclusion: Cancer treatment is still not at reach to the poor and the illiterate. Epidemiological studies targeted at genetic basis of origin will be beneficial in identifying rare, and unusual presentation of the disease. We believe that this case will highlight the importance of risk assessment and early diagnosis of cancer at mass level.
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Mohammed D, Jaber A, Philippe M, Kishore S. Lymphoepithelial carcinoma in the maxillary sinus:A case report. J Med Case Rep. 2012,6:416
Schneider M, Rizzardi C. Lymphoepithelial carcinoma of the Parotid gland and its relationship with Benign Lymphoepithelial Lesions. Arch Pathol Lab Med. 2008,132:278-282
Rytkönen AE, Hirvikoski PP, Salo TA. Lymphoepithelial carcinoma: Two case reports and a systematic review of oral and sinonasal cases. Head Neck Pathol. 201,5:327-334
Wu FY, Yang ES, Willey CD, Ely K, Garrett G, Cmelak AJ et al. Refractory Lymphoepithelial carcinoma of the nasopharynx: A case report illustrating a protracted clinical course. Head Neck Oncol. 2009,1:18
Lester D. R. Thompson. Sinonasal carcinomas. Curr Diagn Pathol. 2006,12:40-53
Spencer CR, Skilbeck CJ, Thway K, Nutting CM. Lymphoepithelial carcinoma of the parotid gland: A rare neck lump. JRSM Short Rep. 2012,3:28
Kimura M, Weiss GH. The stepping stone model of population structure and the decrease of genetic correlation with distance. Genetics. 1964,49:561-576
Liang SB, Deng YM, Zhang N, Lu RL, Zhao H, Chen HY, Li SE et al. Prognostic significance of maximum primary tumor diameter in nasopharyngeal carcinoma. BMC Cancer. 2013,13:260
Vijeev Vasudevan, S Kailasam, M B Radhika, Manjunath Venkatappa, Devaraju Devaiah, T G Shrihari, M Sudhakara. Well-differentiated squamous cell carcinoma of maxillary sinus. J Indian Aca Oral Med Radiol. 2012,24:250-254
Xiao G, Cao Y, Qiu X, Wang W, Wang Y. Influence of gender and age on the survival of patients with nasopharyngeal carcinoma. BMC Cancer. 2013,13:226
David W Kennedy, William E Bolger, S. James Zinreich. Diseases of the Sinuses Diagnosis and Management. Hamilton, B.C. Decker Inc. 2001,93
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