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Case of Primary Carcinosarcoma as an Extremely Rare Cancer of Gallbladder

Seyhan Yalaz, Serap Karaarslan, Aynur Solak, Atİlla ÇÖkmez, Hasan Kaplan

Abstract


Introduction: Gallbladder carcinosarcomas (GBCS) are a rare type of gallbladder malignancies. These tumors are characterized by interlaced epithelial and mesenchymal components.

Presentation of Case: The experience with diagnosis and follow-up of these cancers is limited because of the number of patients diagnosed with this tumor is so small and the tumor has a poor prognosis. Therefore, we present the following case report to share our experience with a 13-month survival of a 55-year-old woman presenting with right flank pain and jaundice who underwent laparoscopic cholecystectomy with an initial diagnosis of chronic cholecystitis and later diagnosed with GBCS.

Conclusion: GBCS have  poor survival rate even with successful surgical therapy due to unclear etiopathogenesis, extremely very low incidence, and lack of consensus regarding its follow-up and treatment.



Keywords


Carcinosarcoma; gallbladder; treatment; prognosis

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References


Zhang L, Chen Z, Fukuma M, Lee LY, Wu M. Prognostic significance of race and tumor size in carcinosarcoma of gallbladder: a meta-analysis of 68 cases. Int J Clin Exp Pathol. 2008, 1:75-83

Kim HH, Hur YH, Jeong EH, Park EK, Koh YS, Kim JC, et al. Carcinosarcoma of the gallbladder: report of two cases. Surg Today. 2012, 42:670-5

Sung BP,Yang HK, Hye LR, Gi BC. Primary carcinosarcoma of the gallbladder. J Korean Surg Soc. 2012, 82:54-8

Huguet KL, Hughes CB, Hewitt WR. Gallbladder carcinosarcoma: a case report and literature review. J Gastrointest Surg. 2005, 9:818-821

Okabayashi T, Sun ZL, Montgomey RA, Hanazaki K. Surgical outcome of carcinosarcoma of the gall bladder: a review. World J Gastroenterol. 2009, 21:4877-4882

Khanna M, Khanna A, Manjari M. Carcinosarcoma of the gallbladder: a case report and review of the literature. J Clin Diagn Res. 2013, 7:560-562

Li BF, Li PW, Shi R, Liu ZL, Liu YF. Clinicopathologic analysis of gallbladder carcinosarcoma. Am Surg. 2013, 79:E37-E39

American Joint Committee on Cancer. Gallbladder. In: AJCC Cancer Staging Manual. 7th ed. New York: Springer; 2010: 211-214

Uzun MA, Koksal N, Gunerhan Y, Celik A, Guneş P. Carcinosarcoma of the gallbladder: report of a case. Surg Today. 2009, 39:168-171

Yamaguchi K, Tsuneyoshi M. Subclinical gallbladder carcinoma. Am J Surg. 1992, 163:382-386

Al-Daraji WI, Makhlouf HR, Miettinen M, Montgomery EA, Goodman ZD, Marwaha JS, et al. Primary gallbladder sarcoma: a clinicopathologic study of 15 cases, heterogeneous sarcomas with poor outcome, except pediatric botryoid rhabdomyosarcoma. Am J Surg Pathol. 2009, 33:826-834


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