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Metachronous Bilateral Adenoid Cystic Carcinoma of the Lacrimal Gland

Mehmet Faik Çetindağ, Yasemin Benderli Cihan, Atiye Yılmaz Ozsavran, Handan Özdemir, Fatih Göksel, Osman Sunter

Abstract


Background: To report an aggressive and treatment-resistant adenoid cystic carcinoma (ACC) of the lacrimal gland (LG).

Case report: A 29-year-old woman with diagnosis of LG-ACC had operations 7 times, radiotherapy 3 times and systemic chemotherapy 2 times. Although she generally responded therapies, the duration of remissions was short lived and the tumor progressed locally and did hematogen metastases.

Conclusion: LG-ACC presents a therapeutic challenge despite its slow growth rate and lower likelihood of lymph-node metastasis. Postoperative radiotherapy with wide margins should be utilized —even after a complete resection— because of persistent recurrences, perineural invasion and hematogenous spread.


 


Keywords


Adenoid cystic carcinoma, lacrimal gland, radiotherapy

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References


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