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“Tumor in tumor”: A Rare Carcinoma Arising in Benign Cystic Teratoma of Ovary

Priti Chatterjee, Sandeep R Mathur, Ruma Ray

Abstract


 

Introduction: Mature cystic teratoma is the most common germ cell tumor of the ovary. Case reports of malignant transformation in these benign tumors have been reported. The most common malignancies arising in the background of mature teratomas are squamous cell carcinoma and adenocarcinoma. Skin appendageal tumors also have been reported of which most are sebaceous carcinomas. .

Case Presentation: A 54-yr-old lady presented with abdominal pain and abdominal mass. Radiological investigations revealed a complex cystic mass in the left ovary. A total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed. Histopathological examination revealed sebaceous carcinoma in-situ arising in a mature cystic teratoma of ovary.

Conclusion: Sebaceous carcinoma in-situ is extremely rare occurrence in mature teratoma of ovary. However it should be keenly looked for as other carcinomas so that the patient can be kept on regular follow up. This is the first report of such a rare occurrence.


Keywords


teratoma; sebaceous carcinoma; sebaceous carcinoma-in-situ; ovary; malignancy

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References


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