Successful Surgical Treatment of a Patient with a Solitary Asymptomatic Cardiac Metastasis from Breast Cancer, Identified by Elevated Tumor Markers and Circulating Tumor Cells
Abstract
Indroduction: Cardiac metastases are a not infrequent autopsy finding in patients dying of metastatic cancer, but are less commonly diagnosed during life (1). Although the autopsy incidence of cardiac metastases ranges may be as high as 25%, solitary cardiac metastases in the absence of metastatic involvement of other organs are rare (2).
Case Presentation: We report here the case of a 66-year old woman with a history of bilateral breast cancer, where a solitary metastasis in the right atrium was successfully resected.
Conclusion: In the absence of any symptoms or clinical findings on physical examination, the presence of metastatic disease was first suggested by the detection of elevated tumor markers and circulating tumor cells during routine follow up after treatment for early stage breast cancer.
Keywords
Full Text:
PDFReferences
Butany J, Nair V, Naseemuddin A, et al. Cardiac tumours: diagnosis and management. Lancet Oncology. 2005, 6(4) : 219-228
Reynen K, Kockeritz U, Strasser RH. Metastases to the heart. Annals of Oncology. 2003, 15 (3): 375-381.
Bussani R, De-Giorgio F, Abbate A, et al. Cardiac metastases. Journal of Clinical Pathology. 2007, 60(1): 27-34
Di Lascio S, Pagani O. Oligometastatic breast cancer: a shift from palliative to potentially curative treatment? Breast Care (Basel, Switzerland). 2014, 9(1):7-14
Salama JK, Chmura SJ. The role of surgery and ablative radiotherapy in oligometastatic breast cancer. Seminars in Oncology. 2014, 41(6):790-797
Noel A, Toquet C, Dewilde J. Prolonged survival after surgery for cardiac metastasis from malignant melanoma. Journal of Cardiology Cases. 2014, 10(4):150-152
Ravikumar TS, topulos GP, Anderson RW, Grage TB. Surgical resection for isolated cardiac metastases. Archives of Surgery. 1983, 118(1):117-120
Owusu C, Harris L. Tumor markers in older patients with early breast cancer: why are we still doing useless tests? Journal of Clinical Oncology. 2015, 33(2):136-137
Khatcheressian JL, Hurley P, Bantug E, et al. Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update. Journal of Clinical Oncology. 2013, 31(7): 961-965
Hojo T, Masuda N, Mizutani T, Shibata T, Kinoshita T, Tamura K, Hara F, Fujisawa T, Inoue K, Saji S, Nakamura K, Fukuda H, Iwata H. Intensive vs. Standard Post-Operative Surveillance in High-Risk Breast Cancer Patients (INSPIRE): Japan Clinical Oncology Group Study JCOG1204. Jpn J Clin Oncol. 2015, 45(10):983-986
Refbacks
- There are currently no refbacks.
