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Non-Alpine Epithelioid Angiosarcoma of Thyroid Gland: A Rare Clinical Scenario

Asad Azim, Fatima Mir, Talat Waseem, Khawaja M. Azim

Abstract


Malignant sarcomatous tumors of thyroid gland of vascular endothelial origin are uncommon. Moreover, epithelioid variety of angiosarcoma of thyroid gland is even rarer and exhibit relatively aggressive oncological behavior especially in Non-Alpine world. Here we report such a case of the thyroid neoplasm which proved to be angiosarcoma of thyroid gland on final immunohistological analysis and was treated with total thyroidectomy followed by adriamycin based chemoradiation. This tumor accours very rarely in Non-alpine region and to the best of our knowledge only 19 cases of such a variety have been previously reported in the literature in form of case reports. We also give a brief review of the literature.


Keywords


Angiosarcoma; Thyroid Gland; Thyroidectomy

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References


Rotellini M, Vezzosi V and Bianchi S. Epithelioid Angiosarcoma of the Thyroid: Report of a Case from an Italian Non-Alpine Area and Review of the Literature. Endocr Pathol. 2015, 26(2):152-156

Mittal A, Kumar S, Singh YB and Garg S. Angiosarcoma Thyroid: Case Report and Review of Literature. Case Reports in Clinical Medicine. 2014, 3:105-109

Maiorana A, Collina G, Cesinaro AM, Fano RA, Eusebi V. Angiomatoid carcinoma of the thyroid: clinicopathological analysis of seven cases from non-Alpine areas. Wirchows Arch. 1996, 429(2-3):131-137

Binesh F, Akhavan A, Navabii H, Dadgarnia MH, Zand V. Primary angiosarcoma of the thyroid gland in an young Iranian woman. BMJ Case rep. 2011, Jun 30.

Ortiz J, Villabona C, Bengoechea O. Primary epithelioid angiosarcoma of the thyroid: an infrequent malignant tumor. Endocrinol Nutr. 2008, 55(4):181-183

Gouveia P, Silva C, Magalhaes F, Santos C, Guerreiro E, Santos F, Gomes T. Non-Alpine thyroid angiosarcoma. Int J Surg Case Rep. 2013, 4(5):524-527

Kalitova P, Plazak J, Kodet R, Astl J. Angiosarcoma of the thyroid. Eur Arch Otorhinolaryngol. 2009, 266: 903-905

Eusebi V. Tumours of the thyroid and parathyroid In: DeLellis RA, Ronald ADL, Ricardo VL. WHO classification of tumours. Tumours of endocrin organs, 8th ed.

Mills SE, Gaffey MJ, Watts JC, Swanson PE, Wick MR, LiVolsi VA, Nappi O, Weiss LM. Angiomatoid carcinoma and ‘angiosarcoma’ of thyroid gland: a spectrum of endothelial differentiation. Am J Clin Pathol. 1994, 102(3):322-330

Tanda F, Massarelli G, Bosincu L, Cossu A. Angiosarcoma of the thyroid: a light, electron microscopic and histoimmunological study. Human Pathol. 1988, 19:742-745

Eusebi V, Carcangiu ML, Dina R, Rosai J. Keratin-positive epithelioid angiosarcoma of thyroid. A report of four cases. Am J Surg Pathol. 1990, 14(8):737-747

Petronella P, Scorzelli M, Luise R, Iannaci G, Sapere P, Ferretti M, Costanzo RM, Freda F, Canonico S, Rossiello R . Primary thyroid angiosarcoma: an unusual localization. World J Surg Oncol. 2012, 10:73

Goh SG, Chuah KL, Goh HK, Chen YY. Two cases of epithelioid angiosarcoma involving the thyroid and a brief review of non-Alpine epithelioid angiosarcoma of the thyroid. Arch Pathol Lab Med. 2003, 127(2):70-73


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