Cover Image

Diffuse Large B-cell Lymphoma during Pregnancy

Yoosef Roosta, Mortaza Raeisi, Kawsar Tarvirdizade, Roya Dolatkhah


Introduction:Non-Hodgkin Lymphoma (NHL) during pregnancy are very uncommon, and primary symptoms of NHL are similar to pregnancy physiologic changes.

Case presentation:We report a case of NHL during pregnancy that didn’t have any peripheral lymphadenopathy, with mediastinal involvement. Chemotherapy began during pregnancy and after delivery treatment continued with chemotherapy and radiotherapy, and mother and baby were both healthy.

Conclusion: Early diagnosis of NHL cause to better prognosis of disease andmaking a chance for mother to make a decision about continue pregnancy or not and about her treatments.


large B-cell; lymphoma; pregnancy

Full Text:



Swierczewski AL, Pasiński J, Estemberg D, Kuś E, Brzozowska M, Kuzmecka-Matuszewska J, et al. Pregnancy and delivery in a patient with non-Hodgkin lymphoma- a case report.Ginekol Pol.2012, (1):57-61

Silva PT, de Almeida HM, Príncipe F, Pereira-Leite L.Non-Hodgkin lymphoma during pregnancy.Eur J Obstet Gynecol Reprod Biol. 1998, 7(2): 249-251

Avivi I, Farbstein D, Brenner B, Horowitz NA.Non-Hodgkin lymphomas in pregnancy: tackling therapeutic quandaries.Blood Rev. 2014, 8(5):213-220

Orkun Ç, Begüm A, Seyfettin U, Cihat F, Ipek DÇ, Hakan E.Non- Hodgkin Lymphoma Diagnosed During Pregnancy: A Case Report.Perinatal Journal. 2011, (2):94-98

Asma H, Moffazel H. Non-Hodgkin’s Lymphoma in Pregnancy.Bangladesh J ObstetGynaecol.2009, 4(1): 27-31

Mark S, Marc C, Carl FI, Bruse S.Non-Hodgkin’s Lymphoma during Pregnancy. Gynecologic oncology. 1991, 43:309-312

Rodriguez JM, Haggag M.VACOP-B chemotherapy for high grade non-Hodgkin's lymphoma in pregnancy. Clinical Oncology. 1995, 7:319-320

Constantinos GM, George JD, Ioannis SP, Aristides JA, Stylianos KM.Non-Hodgkin’s lymphoma during Pregnancy–Case report.European Journal of Obstetrics & Gynecology and Reproductive Biology. 1998, 79:95-97


  • There are currently no refbacks.

AJCC-REP (ISSN 2572-5742)Copyright © 2012-2021. All rights reserved. Published by Ivy Union Publishing, 3204 Valley Rush Dr, Apex, North Carolina 27502, United States