Cover Image

Extraosseous Renal Ewing Sarcoma: The “Blue” Tumour in kidney

Ng Han Kun, Shankaran Thevarajah


Introduction: Primary Ewing sarcoma (ES) is a distinctly rare tumour in the kidney and very limited cases were reported till date.

Case Presentation: Herein, we report a case of right renal ES in a young boy who presented with bleeding right renal tumour and underwent emergency right radical nephrectomy. Tumour cells are strongly positive for CD99 and FLI-1, thus confirming the diagnosis.

Conclusion: Therefore, this entity should always be one of the differential diagnosis while dealing renal masses in young population.


Renal;extraosseus; Ewing’s sarcoma; blue tumour; CD-99, FLI-1

Full Text:



Almeida MF, Patnana M, Korivi BR, et al. Ewing Sarcoma of the kidney: A rare entity. Case Rep Radiol.2014, 2014:283902

Riggi N, Stamenkovic I. The Biology of Ewing Sarcoma. Cancer Lett. 2007, 254: 1-10

Seemayer TA, Thelmo WL, Bolande RP, et al. Peripheral neuroectodermaltumors. PerspectPediatrPatho. 1975, l 2:151-172

Pernick N. CD99. website. Accessed July 13th, 2019

Stuart L. FLI1. website. Accessed July 13th, 2019

Ekram T, Elsayes KM, Cohan RH, and Francis IR. Computed tomography and magnetic resonance features of renal ewing sarcoma. ActaRadiologica. 2008, 49(9):1085-1090

Lalwani N, Prasad SR, Vikram R, Katabathina V, Shanbhogue A, and Restrepo C. Pediatric and adult primary sarcomas of the kidney: a cross-sectional imaging review. ActaRadiologica. 2011, 52(4):448-457

Ellinger J, Bastian PJ, Hauser S, Biermann K, and Müller SC. Primitive neuroectodermaltumor: rare, highly aggressive differential diagnosis in urologic malignancies. Urology. 2006, 68( 2):257-262

Angel JR, Alfred A, Sakhuja A et al. Ewing's sarcoma of the kidney.International Journal of Clinical Oncology. 2010, 15:314-318

Venkitaraman R, Mukkunda R, Thway K et al. Primary adult renal Ewing's Sarcoma: a rare entity. Sarcoma. 2009, 2009:504654

Fergany F, Dhar N, Budd GT, Skacel M, and Garcia J. Primary extraosseousewing sarcoma of the kidney with level III inferior vena cava thrombus. Clinical Genitourinary Cancer. 2009, 7(3):E95-E97

Rizzo D, Barone G, Ruggiero A et al. Massive venous thrombosis of inferior vena cava as primary manifestation of renal Ewing's sarcoma. Clinical Nephrology. 2011, 75(6) :560-564

Jimenez RE, Folpe AL, Lapham RL et al. Primary Ewing's sarcoma/primitive neuroectodermaltumor of the kidney: a clinicopathologic and immunohistochemical analysis of 11 cases. American Journal of Surgical Pathology. 2002, 26(3):320-328

Risi E, Iacovelli R, Altavilla A, et al. Clinical and pathological features of primary neuroectodermaltumor/Ewing Sarcoma of the kidney. Urology. 2013, 82:382-386

Hakky TS, Gonzalvo AA, Lockhart JL, et al. Primary Ewing Sarcoma of the kidney: A symptomatic presentation and review of the literature. TherAdv Urol. 2013, 5:153-159


  • There are currently no refbacks.

AJCC-REP (ISSN 2572-5742)Copyright © 2012-2021. All rights reserved. Published by Ivy Union Publishing, 3204 Valley Rush Dr, Apex, North Carolina 27502, United States