Rectal Carcinoma Metastasis to the Thyroid Gland - the Role of Radiotherapy: A Case Report

Danijela Scepanovic, Mojmir Masar, Andrea Masarykova, Pavol Bires, Marek Paluga, Margita Pobijakova


Introduction: To date,  a very rare occurrence of thyroid metastases from rectal cancer is described  in the literature. Although there are no treatment standards for this condition, surgery still has a major role in the treatment of these patients. However, radiotherapy has a controversial role and its significance is rather palliative.

Case Presentation: We presented a male patient with metastatic rectal carcinoma to the thyroid gland who has been treated with surgery and palliative radiotherapy in our institution.

Conclusion: Although thyroid metastases from rectal cancer are rare, we recommend to think on their potential occurrence what could enable early diagnosis and more successful treatment.


thyroid metastases, rectal carcinoma, radiotherapy

Full Text:



Ozawa T, Saito S, Matsuura S, Kishi H, Maeda M, Watanabe T. Thyroid gland metastasis of rectal cancer. Journal of Surgical Case Reports. 2015, 1-4

Minami S, Inoue K, Irie J, Mine T, Tada N, Hirabaru M, Noda K, Ito S, Haraguchi M. Metastasis of colon cancer to the thyroid and cervical lymph nodes: a case report. Surgical Case Reports. 2016, 2:108

Coelho MI, Albano MN, Costa Almeida CE, Reis LS, Moreira N, Almeida CMC. Colon cancer metastasis to the thyroid gland: A case report. International Journal of Surgery Case Reports. 2017, 37:221-224

Amenduni T, Carbone A and Bruno R. Precocious and isolated thyroid metastasis of colorectal adenocarcinoma and incidental thyroid papillary microcarcinoma. Endocrine. 2014, 47:969-970

Moria K, Koinumaa K, Nishinob H, Horiea H, Kawarai Lefora A, Sata N. Rectal cancer with a metastasis to the thyroid gland: A case report. International Journal of Surgery Case Reports. 2020, 66:39-42

Wood K, Vini L, Harmer C. Metastases to the thyroid gland: the Royal Marsden experience. Eur J Surg Oncol. 2004, 30:583-8

Batson OV. The function of the vertebral veins and their role in the spread of metastases. Clin Orthop Relat Res. 1940, 1995:4-9

Keranmu A, Zheng H, Wu Y, Zhao J, Xu X, Liu F, Cai S, Wang Y, and Xu Y. Comparative study of single-center patients with thyroid metastases from colorectal cancer and previously reported cases in the literature. World Journal of Surgical Oncology. 2017, 15:88

Fujita T, Ogasawara Y, Doihara H, Shimizu N. Rectal adenocarcinoma metastatic to the thyroid gland. Int J Clin Oncol. 2004, 9:515-9

Calzolari F, Sartori PV, and Talarico C, et al. Surgical treatment of intrathyroid metastases: preliminary results of a multicentric study. Anticancer Res. 2008, 28:2885-2888

Luo M, Huang Y, Li Y, et al. Metastatic rectal cancer to papillary thyroid carcinoma: a case report and review of literature. BMC Gastroenterol. 2020, 20:136


  • There are currently no refbacks.

AJCC-REP (ISSN 2572-5742)Copyright © 2012-2021. All rights reserved. Published by Ivy Union Publishing, 3204 Valley Rush Dr, Apex, North Carolina 27502, United States