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Epstein Barr Virus negative Lymphoepithelial Carcinoma Involving the Maxillary Sinus: A Rare Case Report

Muthyam Santan Reddy, Tathagat Singh, Kumar Pushpanshu, Bimleshwar Kumar


Introduction: Lymphoepithelial carcinoma (LEC) is one of the rare malignancies involving the head and neck region. It is common in Eskimos and Chinese population with Epstein Barr virus association. Standard treatment protocol is not in place owing to the rarity of this tumor.

Case Presentation: The present case is a LEC involving the right maxillary sinus not associated with Epstein Barr Virus (EBV) and first of its kind presentation in the Indian population. Lack of awareness, nonaffordability and poor patient compliance resulted in poor response to radiotherapy. The patient succumbed within fourteen months of diagnosis.

Conclusion: Cancer treatment is still not at reach to the poor and the illiterate. Epidemiological studies targeted at genetic basis of origin will be beneficial in identifying rare, and unusual presentation of the disease. We believe that this case will highlight the importance of risk assessment and early diagnosis of cancer at mass level.


Lymphoepithelial carcinoma; Nasopharyngeal carcinoma; Immunohistochemistr; Ohngren’s line; Gene migration

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