
A Rare Case of Metastatic Malignant Melanoma to a Single Site in the Gastrointestinal Tract
Abstract
Introduction: Melanoma is the most malignant skin cancer and has the potential to metastasize to various parts of the body, usually with multi- organ involvement and poor prognosis. Single site metastasis, especially to an intra- abdominal site is rare.
Case Report: Here, we present a patient who had vaginal melanoma which metastasized only to the stomach, with a review of the available literature on diagnostic and treatment options.
Conclusion: Complete resection of gastrointestinal metastasis of malignant melanoma can palliate and may also prolong survival of these patients.
Keywords
Full Text:
PDFReferences
Taal BG, Westerman H, Boot H et al. Clinical and Endoscopic Features of Melanoma Metastases in the Upper GI Tract. Gastrointestinal endoscopy. 1999, Vol 50 No 2
Patel K, Ward ST, Packer T et al. Malignant Melanoma of the Gastrointestinal Tract: A Case Series. International Journal of Surgery. 2014, 12:523-527
Patel JK, Didolkar MS, Pickren JW et al. Metastatic Pattern of Malignant Melanoma. The American Journal of Surgery. 1978, 135:807-810
Dickson PV, Gershenwald JE. Staging and Prognosis of Cutaneous Melanoma. Surg Oncol Clin N Am. 2011, 20(1):1-1
Schuchter LM, Green R, Fraker D. Primary and Metastatic Diseases in Malignant Melanoma of the Gastrointestinal Tract. Current Opinion in Oncology. 2000, 12:181-185
Sanki RA, Scolyer Thompson JF. Surgery for Melanoma Metastases of the Gastrointestinal Tract: Indications and Results. EJSO. 2009, 35:313-319
Reinhardt MJ, Joe AY, Jaeger U et al. Diagnostic Performance of Whole Body Dual Modality 18F-FDG PET/CT Imaging for N- and M- Staging of Malignant Melanoma: Experience with 250 Consecutive Patients. Journal of Clinical Oncology. 2008, 24 (7)
Blecker D, Abraham S, Furth EE et al. Melanoma in the Gastrointestinal Tract. The American Journal of Gastroenterology. 1999, 94( 12)
Liang KV, Sanderson SO, Nowakowski GS et al. Metastatic Malignant Melanoma of the Gastrointestinal Tract. Mayo Clin Proc. 2006, 81(4):511-516
Ricaniadis N, Konstadoulakis MM, Walsh D et al. Gastrointestinal Metastases from Malignant Melanoma. Surgical Oncology. 1995. 4: 105-110
Scolyer RA, Long GV, Thompson JF. Evolving concepts in melanoma classification and their relevance to multidisciplinary melanoma patient care. Molecular oncology. 2011, 5:124-136
Kong Y, Si L, Zhu Y et al. Large-Scale Analysis of KIT Aberrations in Chinese Patients with Melanoma
Goldinger SM, Murer C, Stieger P et al. Targeted Therapy in Melanoma – the Rold of BRAF, RAS and KIT mutations. EJC Supplements. 2013, 11:92-96
Hao M, Song F, Du X et al. Advances in Targeted Therapy for Unresectable Melanoma: New Drugs and Combinations. Cancer letters. 2015, 359 :1-8
Refbacks
- There are currently no refbacks.