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Breast Metastasis from Differentiated Thyroid Carcinoma Primary: A Case Report and Review of Literature

Kevin C. Brown, Ryan B. Fransman, Nisha Lakhi, Preeti Gupta, Michael S. Ballo, Eugene Meyer


Introduction: Metastasis to the breast from non-mammary malignancy is rare, with a reported incidence of less than 1%[2-4]. Aside from hematologic malignancies and contralateral breast cancer, the most common primary malignancies that metastasize to the breast are lung, ovarian, gastrointestinal cancers, and melanoma.

Presentation of Case: We present an 82-year-old female with metastatic breast cancer arising from a primary papillary thyroid carcinoma. She presented with a palpable right breast mass 4 years after resection and treatment of a primary thyroid cancer.

Conclusion: Ultrasound guided core biopsy and immunohistochemical staining demonstrated metastatic papillary thyroid carcinoma. The patient underwent lymphoscintigraphy and subsequent resection of the breast mass along with two axillary lymph nodes.


Breast; Metastasis; Carcinoma; Metastasis; Thyroid

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