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Epithelioid Trophoblastic Tumor (ETT) Confined to the Uterus: A Case Report and Brief Literature Review

Daniel Vilarim Araújo, Aline Fusco Fares, Leonardo Boente, Daniel Garcia, Marcello Ferretti Fanelli, Solange M Sanches


Introduction: ETT is a rare entity, with few reports in the literature. There is no prospective data regarding this issue and its management is based in retrospective series of cases and specialists opinion.

Case presentation: We present a case of a 33 years old woman, 5 pregnancies (3 para) who presented with spontaneous vaginal bleeding after an abortion. Pelvic  MRI revealed  uterus of 162 cm3, and a nodular lesion of 4,3x 4,1x3,3cm in isthmus, compromising uterine cavity. She underwent a hysteroscopy whose biopsy material was highly necrotic, with proliferative pattern but no malignancy identified. Next was performed a Laparoscopic total hysterectomy plus bilateral salpingo-oophorectomy with a pathological finding of ETT confined to the uterus. The hCG level was undetectable. We decided to put the patient on follow up. 

Conclusion: Management of ETT is a challenge due to its rarity and diverse presentation, requiring efforts on grouping cases together in order to understand its evolution.


Epithelioid Trophoblastic Tumor; Gestational Trophoblastic Disease;

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