Cover Image

Incidental Finding of Benign Multicystic Peritoneal Mesothelioma: A Case Report

Lauren Nosanov, Nikhil Chervu, Paul Sugarbaker, Chukwuemeka Ihemelandu


Introduction: Benign multicystic peritoneal mesothelioma represents a rare benign variant of peritoneal mesothelioma, with fewer than 150 cases reported to date. Malignant transformation may occur. We present a patient with an incidental finding of an intra-abdominal mass consistent with benign multicystic peritoneal mesothelioma.

Case presentation: A 51 year-old male presented to the ED with traumatic injuries. During workup, calcified cystic lesions in the pelvis were incidentally noted. Final pathology favored a diagnosis of benign multicystic mesothelioma of the peritoneum. Follow-up imaging obtained three months post-operatively revealed no evidence of recurrent or metastatic disease.

Conclusion: Multicystic peritoneal mesothelioma has been identified as a distinct subtype of peritoneal mesothelioma, with long-term survival achievable through the use of cytoreductive surgery and HIPEC. Although prognosis is relatively favorable, recurrence rates are high, with low potential for malignant transformation. Post-operative surveillance with routine imaging is warranted.


benign multicystic peritoneal mesothelioma; BMPM; peritoneum

Full Text:



Aber A, Tahir A, Arumuham V, Smith G, and Almpanis S. Benign cystic mesothelioma: a rare cause for scrotal swelling. Case Rep Med. 2012, 2012: 572186

Iacoponi S, Calleja J, Hernandez G, and Sainz De La Cuesta R. Asymptomatic peritoneal carcinomatosis originating from benign cystic peritoneal mesothelioma. Ecancermedicalscience. 2015, 9:605

Charfi S, Chetaille B, Marcy M, Turrini O, Maison CDC, Delpero JR, et al. Multicystic peritoneal mesothelioma: Report of three cases. Pathologica. 2008, 100:416-419

Datta R V., and Paty PB. Cystic mesothelioma of the peritoneum. Eur J Surg Oncol. 1997, 23:461-462

Momeni M, Pereira E, Grigoryan G, and Zakashansky K. Multicystic benign cystic mesothelioma presenting as a pelvic mass. Case Rep Obstet Gynecol. 2014, 2014:852583

Yeom S, Son T, and Hong YO. Complicated benign cystic mesothelioma of mesoappendix misdiagnosed as an appendiceal abscess in a postpartum period woman. Ann Sur Treat Res. 2015, 88:170-173

Somasundaram S, Khajanchi M, Vaja T, Jajoo B, and Dey AK. Benign multicystic peritoneal mesothelioma: a rare tumour of the abdomen. Case Rep Surg. 2015, 2015:613148

Tamhankar VA. Multicystic Benign Mesothelioma Complicating Pregnancy. Case Rep Obstet Gynecol. 2015, 2015:1-3

Pitta X, Andreadis E, Ekonomou A, Papachristodoulou A, Tziouvaras C, Papapaulou L, et al. Benign multicystic peritoneal mesothelioma: a case report. J Med Case Rep. 2010, 4:385

Baddoura FK, and Varma VA. Cytologic findings in multicystic peritoneal mesothelioma. Acta Cytol. 1990, 34:524-528

Bui-Mansfield LT, Kim-Ahn G, and O’Bryant LK. Multicystic mesothelioma of the peritoneum. Am J Roentgenol. 2002, 178:402

Occhionorelli S, Tartarini D, Pascale G, Maccatrozzo S, Stano R, and Vasquez G. Benign multicystic mesothelioma of peritoneum complicating acute appendicitis in a man: a case report. J Med Case Rep. 2016, 10:44

Tentes AA, Zorbas G, Pallas N, and Surgical AF. Multicystic peritoneal mesothelioma. Am J Case Rep. 2012, 13:262-264

Baratti D, Kusamura S, Sironi A, Cabras A, Fumagalli L, Laterza B, et al. Multicystic peritoneal mesothelioma treated by surgical cytoreduction and hyperthermic intra-peritoneal chemotherapy (HIPEC). In Vivo (Brooklyn). 2008, 22:153-158

Pocard M. Intra-abdominal benign multicystic peritoneal mesothelioma. J Visc Surg. 2014, 151:155-157

O’Connor DB, Beddy D, and Aremu MA. Benign cystic mesothelioma of the appendix presenting in a woman: a case report. J Med Case Rep. 2010, 4:394

Jerbi M, Hidar S, Ziadi S, and Khairi H. Benign multicystic peritoneal mesothelioma. Int J Gynecol Obstet. 2006, 93:267-268

Pelosi G, Zannoni M, Caprioli F, Faccincani L, Battistoni MG, Balercia G, et al. Benign multicystic mesothelial proliferation of the peritoneum: immunohistochemical and electron microscopical study of a case and review of the literature. Histol Histopathol. 1991, 6:575-583

Cusatelli P, Altavilla G, and Marchetti M. Benign cystic mesothelioma of peritoneum: a case report. Eur J Gynaecol Oncol. 1997, 18:124-126

Staniscia G, Tidona V, Sardellone A, and De Nicola E. Benign peritoneal multicystic mesothelioma. Ann Ital Chir. 2003, 74:579-582

Gonzalez-Moreno S, Yan H, Alcorn KW, and Sugarbaker PH. Malignant transformation of “benign” cystic mesothelioma of the peritoneum. J Surg Oncol. 2002, 79:243-251

Iversen OH, Hovig T, and Brandtzaeg P, Peritoneal, benign, cystic mesothelioma with free-floating cysts, re-examined by new methods. A case report. APMIS. 1988, 96:123-127


  • There are currently no refbacks.

AJCC-REP (ISSN 2572-5742)Copyright © 2012-2021. All rights reserved. Published by Ivy Union Publishing, 3204 Valley Rush Dr, Apex, North Carolina 27502, United States